The cheapest semaglutide programmes

We priced every semaglutide programme we could get a straight answer out of, added the fees they charge behind the advertised rate, and sorted the list cheapest first. The spread between top and bottom is $3,588 a year.

Coreage Rx is cheapest at $1,788 a year. Ro is dearest at $5,376. Same class of medication in both cases — the difference is almost entirely how each company structures its fees.

Every semaglutide programme, cheapest first

Prices verified 2026-09-18. "What you actually pay" includes any membership or platform fee charged alongside the medication.

1. Coreage Rx — $1,788 a year

$149 a month, no membership fee. Eden advertises $99 semaglutide. Mochi advertises $99 semaglutide. Both then bill a membership — $99 a month at Eden, $79 at Mochi — which lands the real figure near $198 and $178. Coreage Rx charges no membership at all, so the advert and the invoice agree.

Costs $600 a year more than the cheapest option. The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year. Full numbers in our Coreage Rx semaglutide review.

2. Trimi — $1,188 a year

$99 a month, no membership fee. Three programmes advertise $99 semaglutide. Trimi and Coreage Rx charge it. Eden bills roughly $198 once its membership renews and Mochi about $178. The headline is identical; the statement is not.

Nothing here is cheaper. Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months. Full numbers in our Trimi semaglutide review.

3. Zealthy — $1,812 a year

$151 a month, no membership fee. Most of this market advertises a low medication price and recovers the difference in a monthly fee. Zealthy does not, so the $151 you are quoted is the $151 you pay.

Costs $624 a year more than the cheapest option. The widely quoted $25/month is an insured price. Cash payers should plan on $151+ for semaglutide. Full numbers in our Zealthy semaglutide review.

4. Mochi Health — $2,136 a year

$178 a month, including the $79 fee. Mochi and Eden advertise exactly the same $99 medication price. Mochi’s membership is $79 against Eden’s $99, so Mochi is about $240 a year cheaper and includes an insurance team Eden does not.

Costs $948 a year more than the cheapest option. Labs are billed separately. Ask what the clinic expects to order before you sign up. Full numbers in our Mochi Health semaglutide review.

5. Hims & Hers — $2,256 a year

$188 a month, including the $39 fee. That gap between the advertised figure and the injectable figure is the single most misread thing about this company. Oral and injectable GLP-1s are not interchangeable products, and comparing a $79 oral kit against a $99 weekly injection is comparing two different treatments on one axis.

Costs $1,068 a year more than the cheapest option. The advertised entry prices and the membership are separate charges. Add $39/month to whatever medication figure you were quoted. Full numbers in our Hims & Hers semaglutide review.

6. PlexusDx — $2,268 a year

$189 a month, no membership fee. More than the $99 leaders and less than every membership-charging programme in the table. What the difference buys is verifiability — six named pharmacies and named prescribers, published rather than implied.

Costs $1,080 a year more than the cheapest option. The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier. Full numbers in our PlexusDx semaglutide review.

7. Eden — $2,376 a year

$198 a month, including the $99 fee. The difference is entirely the membership — $39 to start, $99 a month thereafter. It is disclosed, it is legal, and it doubles your bill. This is the clearest example on our whole site of why an advertised price is worth almost nothing on its own.

Costs $1,188 a year more than the cheapest option. The $99 semaglutide headline becomes roughly $198/month once the membership renews at its ongoing rate. Full numbers in our Eden semaglutide review.

8. Ivím Health — $2,388 a year

$199 a month, no membership fee. Semaglutide is usually the choice of people who want the gentler drug, often after a bad experience. Pairing it with a programme built around frequent clinical contact makes more sense than the price comparison alone suggests.

Costs $1,200 a year more than the cheapest option. Pharmacy sourcing is not published. Ask which pharmacy fills your prescription and whether it is 503A or 503B before starting. Full numbers in our Ivím Health semaglutide review.

Two programmes we leave out of this table

A price table only works if every row is a price for the same thing. Two are not, so we hold them out and say why: LifeMD — the monthly charge buys clinical care and insurance work, not medication — the drug is billed separately; Noom Med — medication is included, but at deliberately low doses well below those used in the trials; WeightWatchers Clinic — the monthly charge buys clinical care and insurance work, not medication — the drug is billed separately.

Both can be the right choice — LifeMD is excellent if your insurer will cover the medication, and Noom has the best coaching here. Neither belongs in a like-for-like price sort against a programme that includes the drug.

Six ways these prices hide

1. The renewing membership. A $39 introductory fee becomes $99 a month. Eden is the clearest example.
2. The fee quoted separately. Hims & Hers advertises $199 medication and bills $39 membership beside it.
3. The fee that buys no medication. Ro charges $149 a month for care only.
4. The cheapest tier that is a different product. "From $179" at Henry Meds is sublingual, not the weekly injection.
5. The price that climbs with your dose. Many programmes charge more as you titrate up to a useful dose.
6. The insured price quoted at cash payers. Those $25 a month figures require your plan to approve the prescription.

We walk through each of these with worked examples in how to cut your GLP-1 bill.

What semaglutide is, briefly

A weekly injection that activates the GLP-1 receptor, slowing stomach emptying and reducing appetite signalling.

In STEP-1, adults on 2.4 mg lost an average of about 14.9% of body weight over 68 weeks.

In the SURMOUNT-5 head-to-head trial semaglutide produced less weight loss than tirzepatide, averaging 33.1 lb (15.0 kg) against 50.3 lb (22.8 kg). If you are choosing between the two drugs on price, we compare them in tirzepatide vs semaglutide.

Common side effects: Nausea, vomiting, diarrhoea and constipation, usually worst in the first weeks and after dose increases.

Brand-name prices, for comparison

Through NovoCare, Wegovy has been offered at $199/month for the first two fills through 31 December 2026, then $349/month for 0.25-2.4 mg doses. The oral form is listed between $149 and $299/month by dose.

Those are the FDA-approved products. Compounded versions are not reviewed by the FDA for safety, effectiveness or manufacturing quality — a real difference, and one worth understanding before choosing on price alone. See is compounded still legal.

How we ranked this

• True monthly cost (30%) — What you actually pay in month two — medication plus membership plus anything billed separately. Advertised teaser rates score nothing here.
• Price honesty (20%) — Whether the renewal price is visible before you hand over a card, and whether the number at checkout matches the number in the ad.
• Clinical support (20%) — Who prescribes, how you reach them between visits, and whether dose changes are reviewed by a person or applied on a schedule.
• Pharmacy sourcing (15%) — Whether the provider names its pharmacy, states the 503A/503B pathway, and offers FDA-approved options alongside compounded ones.
• Cancelling (15%) — How hard it is to stop. Prepaid multi-month plans that cannot be refunded are marked down here.

Coreage Rx pays us and holds the top slot in this table. Everything below it is in true cheapest-first order, the prices are exactly what we verified, and the programmes that undercut our featured pick are named in the section above rather than quietly dropped. Full terms on our disclosure page.